My research is focused on using high-throughput mass spectrometry to study age-related changes in protein expression from the cellular to organism level, and to identify bio-markers for aging. I have particular interest in neurodegenerative diseases and activity-based proteomics in relation to aging.
I have previously worked on biomarker discovery for neurodegenerative diseases like Parkinson’s and Huntington’s disease at Caprion Proteomics. I used high throughput mass spectrometry to profile proteins in body fluids and tissues to quantify differences between healthy and disease. During my postdoctoral work at Harvard Medical School, in Steven Gygi’s Lab, I did proteomics method development relating to phosphoproteomics and kinome profiling. My doctoral work focused on protein profiling in saliva and activity-based proteomics.