Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen

Yunsong Tong, Kenton A Baker, Alex M Chapman, Nathaniel L Elsen, Faith Fowler, Mariam D George, Nathan J Gesmundo, Harry Hatton, Michael Hickey, Charles W Hutchins, Cynthia L Jeffries, Aileen Kelly, Alla Korepanova, Iain R Miller, Boguslaw Nocek, Sanjay C Panchal, Orville A Pemberton, Wei Qiu, Nari N Talaty, Henry Yue Hin Tang, Danli Towne, Maomao Zhang, Yiming Zhao, Sujatha M Gopalakrishnan, Chaohong Sun, Michael E Kort, Michael J Dart, Ari J Firestone