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Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint

Hsiao-Wei Tsao, Seth Anderson, Kenneth J. Finn, Jonathan J. Perera, Lomax F. Pass, Emily M. Schneider, Aiping Jiang, Rachel Fetterman, Cun Lan Chuong, Kaiya Kozuma, Marcia M. Stickler, Marc Creixell, Susan Klaeger, Kshiti Meera Phulphagar, Suzanna Rachimi, Eva K. Verzani, Niclas Olsson, Juan Dubrot, Matthew F. Pech, Whitney Silkworth, Sarah Kate Lane-Reticker, Peter M. Allen, Kyrellos Ibrahim, Nelson H. Knudsen, Andrew Y. Cheng, Adrienne H. Long, Hakimeh Ebrahimi-Nik, Sarah Y. Kim, Peter P. Du, Arvin Iracheta-Vellve, Emily J. Robitschek, Juliette S.M.T. Suermondt, Thomas G.R. Davis, Clara H. Wolfe, Trisha Atluri, Kira E. Olander, Jason S. Rush, Thomas B. Sundberg, Fiona E. McAllister, Jennifer G. Abelin, Ari Firestone, David Stokoe, Steven A. Carr, Fiona A. Harding, Kathleen B. Yates, and Robert T. Manguso
Immunity November 18, 2024