About
Jonathan’s lab focuses on discovering new biology, discovering novel targets and drug development in the areas of immunology, immunometabolism, cancer and aging.
Prior to joining Calico, Jonathan spent 20 years at Johns Hopkins University where, as a physician-scientist, his lab sought to understand how immune cells integrate signals from the immune micro-environment to promote differentiation and function. This work identified a critical role for mTOR in contributing to this process and focused on the metabolic programs that regulate immune responses to cancer.
Jonathan earned his Bachelor of Arts in Biochemistry from Dartmouth College and an M.D. Ph.D. in Immunology from the Emory University School of Medicine. He completed a residency at Johns Hopkins University followed by a clinical fellowship in hematology and oncology and Brigham and Women’s Hospital. He then went on to a post-doctoral fellowship in immunology in the lab of Ronald Schwartz at the National Institute of Allergy and Infectious Diseases, National Institutes of Health. He is a board-certified oncologist.