Lab Automation Engineer 1

  • South San Francisco, CA
  • Full Time
  • R&D

Who we are:

Calico is a research and development company whose mission is to understand the biology of aging, and to help people to lead longer and healthier lives. We aim to combine the best biomedical science with cutting edge technology and computing. We are a nimble, fast-paced startup, while also having secure, long-term funding.

Position description:

Calico is seeking an experienced and motivated Lab Automation Engineer to join our laboratory automation team. This position will support internal research groups, migrating assays and processes from bench-top to automated liquid handling systems and integrated robotic platforms. Assay migration is highly collaborative and the candidate must be able to work with scientists of all levels, have a keen attention to detail, and effectively communicate progress and results. Above all, the ability to troubleshoot and solve problems while maintaining a positive attitude is critical to success in this position.

Position requirements:

  • Significant experience programming automated liquid handling systems (e.g. Tecan EVO or Fluent, Agilent Bravo, Beckman Coulter FX/NX, Hamilton STAR or Vantage)
  • Experience with protocol development and operation of integrated robotic systems and automation scheduling software
  • Hands-on experience with assay development on automated systems: liquid handling performance qualification, biological assay optimization, and inter-/intra- assay performance validation
  • Experience defining liquid classes, labware dimensions, robot teachpoints, and motion vectors
  • Able to troubleshoot and proactively maintain automation equipment
  • Experience with microbiology, molecular biology, flow cytometry, high content analysis, high throughput screening, genomics and sequencing, mass spectrometry, and/or any other standard life-science laboratory workflows
  • BS/MS in science or engineering discipline, minimum 3 years of relevant experience, PhD not require

Additional preferred skills and experience:

  • Software development: desktop, web, mobile, database, or embedded using any programming language
  • Mechanical design using CAD software and rapid prototyping with 3D printers, laser cutters, and/or CNC mills
  • Basic electronic circuit design, layout, and assembly
  • Experience with statistics and data analysis software, especially data reduction and visualization 


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