An automated, home-cage, video monitoring-based mouse frailty index detects age-associated morbidity in C57BL and Diversity Outbred mice

J Graham Ruby, PhD, Andrea Di Francesco, PhD, Paulo Ylagan, BS, Angela Luo, BA, Robert Keyser, BS, Owen Williams, BA, Sarah Spock, BS, Wenzhou Li, PhD, Nalien Vongtharangsy, BS, Sandip Chatterjee, PhD, Cricket A Sloan, MS, MS, Charles Ledogar, MEng, Veronica Kuiper, BS, Janessa Kite, MSc, Marcelo Cosino, Paulyn Cha, BS, Eleanor M Karlsson, DVM