Fiona uses high-throughput mass spectrometry to study age-related changes in protein expression from the cellular to organism level, and to identify biomarkers for aging. She has a particular interest in post translational modifications and how they change in aging and aging-related diseases such as kidney disease and neurodegenerative diseases.
Fiona previously worked on biomarker discovery for neurodegenerative diseases like Parkinson’s and Huntington’s disease at Caprion Proteomics. She used high throughput mass spectrometry to profile proteins in body fluids and tissues to quantify differences between healthy and disease. During her postdoctoral work at Harvard Medical School, in Steven Gygi’s Lab, she performed proteomics method development relating to phosphoproteomics and kinome profiling. Her doctoral work focused on protein profiling in saliva and activity-based proteomics.