Principal Investigator, Quantitative/Systems Biology of Aging

  • South San Francisco, CA
  • Full Time
  • R&D

Who we are:

Calico is a research and development company whose mission is to harness advanced technologies to increase our understanding of the biology of aging. Our longer term mission will utilize this knowledge to devise interventions that enable people to lead longer and healthier lives. Executing on this mission will require an unprecedented level of interdisciplinary effort and a long-term focus for which funding is already in place.

Position description:

Within our academic-style research arm, we seek a Principal Investigator with an innovative basic research program applying quantitative and systems biological approaches to study mechanisms by which adult somatic cells enter and persist in an altered phenotypic state. While applicants utilizing mammalian model systems are preferred, those taking novel approaches in other metazoan systems will also be considered.

Principal Investigators at Calico form and lead small, independent research groups and are expected to directly conduct research. They will play a leadership role in advancing Calico’s overall mission.

Position requirements:

First time or experienced Principal Investigators are welcome to apply. Applicants for first time Principal Investigators should hold a PhD or MD/PhD (or equivalent), have received appropriate postdoctoral training and have a strong record of impact and research productivity. Experienced Principal Investigators must have a proven record of innovative research.

Those applying as first time Principal Investigators should submit a brief research plan and also have three letters of recommendation sent on their behalf. Letters of recommendation can be sent to

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